Anti-HEV IgG is a serologic test that detects IgG-class antibodies to hepatitis E virus (HEV). It is used to determine past exposure to HEV, which can cause acute hepatitis E infection. Anti-HEV IgG usually persists for many years after infection, while anti-HEV IgM indicates recent or ongoing infection. The test can be performed on human serum or plasma samples using an enzyme-linked immunosorbent assay (ELISA).